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100 µl

Ref. YIF-LF-MA0127

photos non contractuelles

Neuf 331.00 H.T.


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Détails Produit

Product description: Monoclonal Antibody. Recognizes the Human protein. Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. Apolipoprotien A-I (Apo A-I) is one of the major protein components in high density lipoprotein (HDL). The molecular weight is reported to be 28.3 kDa. Apo A-I acts as a cofactor for lecithin cholesterol acyl transferase (LCAT), which is important in removing excess cholesterol from tissues and incorporating it into HDL for reverse transport to the liver. Some of the apolipoproteins act as ligands to tissue receptors, while others activate or inhibit enzymes involved in metabolic steps in the circulation or tissues. Apo A-I plays important roles in atherosclerosis, tangier disease, coronary heart disease. Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.

Alternate Names/Synonyms: APOA1

Product Type: Monoclonal Antibody

Clone: 2G4

Isotype: Mouse IgG1 kappa

Immunogen: Purified human Apolipoprotein A-I protein.

Applications: ELISA, IHC, WB

Species Crossreactivity: Human

Formulation: Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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Literature References: 1) G. Walldius et al. (2004) Journal of Internal Medicine 255: 188-205. (General)2) Yves L. Marcel et al. (2003) Genetics and Molecular Biology 14:151-157. (General)