anti-beta-Actin (N-term), pAb

Product description: Polyclonal Antibody. Recognizes the Human, Mouse, Rat protein. Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. Actin is an abundant cytoskeletal protein found in all mammalian cells. Six distinct actin isotypes have been identified in mammalian cells. Each is encoded by a separated gene and is expressed in a developmentally regulated and tissue-specific manner. alpha and beta-cytoplasmic actins are expressed in a wide variety of cells. Whereas, expression of alpha-skeletal, alpha-cardiac, alpha-vascular and gamma-enteric actins are more restricted to specialized muscle cell type. Actin's filaments form part of the cytoskeleton and play essential roles in regulating cell shape and movement. Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

Alternate Names/Synonyms: ACTB; Loading Control

Product Type: Polyclonal Antibody

Immunogen: Synthetic peptide (KLH coupled) corresponding to N-terminal residues of human beta actin.

Applications: WB

Species Crossreactivity: Human, Mouse, Rat

Concentration: 1 mg/ml

Formulation: Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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Literature References: 1) True, L.D. Atlas of Diagositc Immunopathology. (1990) Gower Medical Publishing. N.Y.6.5. (General)2) Otey C et al. J.Cell Biol. (1986) vol.102: pp.1726-1737. (General)3) Reddy S et al. J.Biol. Chem. (1990) vol.262: pp.1863-1867. (General)