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100 µl

Ref. YIF-LF-MA0269
AB FRONTIER

photos non contractuelles

Neuf 331.00 H.T.

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Détails Produit

Product description: Monoclonal Antibody. Recognizes the Human protein. Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. Human chorionic gonadotropin (hCG) is a peptide hormone produced in pregnancy. Its role is to prevent the disintegration of the corpus luteum of the ovary, thereby to maintain progesterone production that is critical for a pregnancy. hCG is a heterodimeric glycoprotein hormone of placental origin, composed of 237 amino acids, with a molecular mass of 36.7 kD. hCG consists of noncovalently associated alpha and beta subunits. The peptide moiety of the alpha subunit is common to the pituitary glycoprotein hormones, luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH), whereas the beta subunit is specific to each particular hormone. Early pregnancy testing, in general, is based on the detection or measurement of beta-hCG. Because beta-hCG is produced also by some kinds of tumor including choriocarcinoma, germ cell tumors, teratoma, beta-hCG is an important tumor marker. hCG has been identified by immunohistochemical methods in prostate, bladder, testicular, colorectal, ovarian, and other cancers. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.

Alternate Names/Synonyms: CGB; CGB3; CG-beta; Choriogonadotropin Subunit beta; Chorionic Gonadotrophin Chain beta

Product Type: Monoclonal Antibody

Clone: 7H4

Isotype: Mouse IgG1 kappa

Immunogen: Human chorionic gonadtropin protein.

Applications: ELISA, WB

Species Crossreactivity: Human

Formulation: Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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Literature References: 1) Thwaini A et al. (2006) Urol Int. 2006;77(4):289-296 (General)2) Okamoto T et al. (2001) J Endocrinol. 171(3):435-443. (General)3) Birken S et al. (1988) Endocrinology. 123(1):572-583. (General)