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100 µl

Ref. YIF-LF-MA0046
ABFRONTIER

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Neuf 321.00 H.T.
en stock

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Détails Produit

Product description: Epitope tags can be used to label and detect proteins with immunoblotting, immunoprecipitation and immunostaining techniques. Due to their small size, they are unlikely to affect the tagged proteina's biochemical properties. The Myc epitope tag is widely used to detect expression of recombinant proteins in bacteria, yeast, insect and mammalian cell systems. Myc proteins are nuclear proteins with relatively short half-lives. Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas. Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.

Alternate Names/Synonyms: MYC; bHLHe39; BHLHE39; Proto-Oncogene c-Myc; Transcription Factor p64; Myc Proto-Oncogene Protein; Class E Basic Helix-Loop-Helix Protein 39; Epitope Tag

Product Type: Monoclonal Antibody

Clone: LF10E3

Isotype: Mouse IgG1 kappa

Immunogen: Synthetic peptide.

Applications: IP, WB

Species Crossreactivity: Human

Formulation: Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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Literature References: 1) Evan, G.I. et al. (1985) Mol. Cell. Biol. 5: 3610-3616. (General)2) Munro, S. and Pelham, H.R. (1984) EMBO J.3: 3087-3093. (General)3) Alitalo, K. et al. (1983) Proc. Natl. Acad. Sci.USA 80: 1707-1711. (General)