anti-Chromogranin A, mAb (23A1)

Product description: Monoclonal Antibody. Recognizes the Human protein. Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. Chromogranin A (CGA) was identified as a major soluble protein in adrenal medullary chromaffin granules. CHGA derived peptides are also known as Catestatin, Vasostatin-I,-II, Prochromacin, Pancreastatin and Parastatin. CGA and its processed products are involved in the biogenesis of densecore secretory granules and have a role in immunity against microbes, and function as potential markers for several types of tumors. They have also been implicated in neurodegenerative disorders and cardiovascular diseases such as a hypertension. CGA accumulates in the senile and preamyloid plaques of Alzheimer°s disease, in Lewy bodies of Parkinson°s disease, and in the swollen neurons of Pick°s disease. Pancreastatin strongly inhibits glucose induced insulin release from the pancreas.

Alternate Names/Synonyms: CHGA

Product Type: Monoclonal Antibody

Clone: 23A1

Isotype: Mouse IgG2b kappa

Immunogen: Recombinant human CGA protein purified from E. coli.

Applications: WB

Species Crossreactivity: Human

Formulation: Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

Lien vers la Fiche Technique

Literature References: 1) Steinbrenner, H. et al (2006) Free Radic. Biol. Med. 40: 1513-1523. (General)2) Burk, R.F. et al (2005) Annu. Rev. Nutr. 25: 215-235. (General)