anti-CSPS (Catecholamine-sulfating Phenol Sulfotransferase), pAb

Product description: Polyclonal Antibody. Recognizes the Human protein. Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. The human Catecholamine-Sulfating Phenol Sulfotransferase (CSPS) is the only sulfotransferase that catalyses the sulfation of catecholamins, in particular the neurotransmitter dopamine, with high activity. CSPS is required for stimulation by Mn2+ of the sulfating activity and expressed in the human intestine, brain, platelet and other tissues. In the brain it may play a role in regulating the levels of dopamine. It also serves as a detoxifying function in the intestine, where it may detoxify potentially lethal dietary monoamines. Catalyzes the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs.

Alternate Names/Synonyms: STM; M-PST; HAST3; TL-PST; SULT1A3; EC=2.8.2.1; ST1A3/ST1A4; Sulfotransferase 1A3/1A4; Aryl Sulfotransferase 1A3/1A4; Placental Estrogen Sulfotransferase; Thermolabile Phenol Sulfotransferase

Product Type: Polyclonal Antibody

Immunogen: Recombinant human protein purified from E. coli.

Applications: WB

Species Crossreactivity: Human

Formulation: Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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Literature References: 1) Pai, T.G. et al. (2003) J. Biol. Chem. 278, 1525-1532. (General)2) Pai, T.G. et al. (2002) J. Biol. Chem. 277,43813-43820. (General)3) Coughtrie, M.W.H. (2002) Pharmacogenomics J. 2, 297-308. (General)