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1x96 wells

Ref. YIF-LF-EK0297
AB FRONTIER

photos non contractuelles

Neuf 425.00 H.T.

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Détails Produit

Product description: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL-23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12.

Alternate Names/Synonyms: IL12B; NKSF2; IL-12B; CLMF P40; IL-12 Subunit P40; Interleukin-12 Subunit beta; NK Cell Stimulatory Factor Chain 2; Cytotoxic Lymphocyte Maturation Factor 40 kDa Subunit

Product Type: Kit

Crossreactivity: Mouse

Sensitivity: 2.898 pg/ml

Range: 15.625 pg/ml - 1000 pg/ml

Sample Type: Mouse Serum, Plasma, Cell Lysate, Culture Supernatants, Buffered Solution

Assay Type: Sandwich

Detection Type: Colorimetric

Short Term Storage: +4°C

Long Term Storage: +4°C

Shipping: BLUE ICE

Handling Advice Any unused reconstituted standard should be discarded or frozen at -80°C. Standard can be frozen and thawed one time only without loss of immunoreactivity.

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Manuel Kit