Cymax IL-4 (mouse) ELISA Kit

Product description: Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1 and IL-6 by macrophages.

Alternate Names/Synonyms: Il4; IL-4; Il-4; BSF-1; Interleukin-4; IGG1 Induction Factor; B-Cell Growth Factor 1; B-Cell Stimulatory Factor 1; Lymphocyte Stimulatory Factor 1; B-Cell IgG Differentiation Factor

Product Type: Kit

Crossreactivity: Mouse

Sensitivity: 0.707 pg/ml

Range: 7.8 pg/ml - 500 pg/ml

Sample Type: Mouse Serum, Plasma, Cell Lysate, Culture Supernatants, Buffered Solution

Assay Type: Sandwich

Detection Type: Colorimetric

Short Term Storage: +4°C

Long Term Storage: +4°C

Shipping: BLUE ICE

Handling Advice Any unused reconstituted standard should be discarded or frozen at -80°C. Standard can be frozen and thawed one time only without loss of immunoreactivity.

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