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10 µg

Ref. YIF-LF-P0270

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Neuf 327.00 H.T.


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Détails Produit

Product Description: Granulocyte colony-stimulating factor (G-CSF) is a hematopoietic cytokine that promotes the proliferation and differentiation of cells in the granulocyte lineage. It is produced mainly by monocytes and macrophages upon activation by endotoxin, TNF-alpha and IFN-gamma. Other cells can also secrete G-CSF after IL-1beta,TNF-alpha and LPS activation. In addition, various carcinoma cell lines and myeloblastic leukemia cells can express G-CSF constitutively. G-CSF has a effect in the treatment of leukopenia, AIDS, MDS and bone marrow transplantation. In humans, two distinct cDNA clones for G-CSF, encoding 207 and 204 amino acid precursor proteins, have been isolated. Both protein have identical amino acid sequences except for a three amino acid insertion (deletion) at the 35th amino acid residue from the N-terminus of the mature protein.

Alternate Names/Synonyms: CSF3; G-CSF; C17orf33; Filgrastim; Lenograstim; Pluripoietin; Granulocyte Colony-stimulating Factor

Product type: Protein

Source / Host: E. coli

Species Crossreactivity: Human

Biological Activity: The ED50 of G-CSF is typically 5-40 pg/ml. Measured in a cell proliferation assay using a murine myeloblastic cell line, NFS-60.

Purity: >95% (SDS-PAGE)

Concentration: 0.5 mg/ml

Formulation: Liquid in PBS, 10% glycerol.

Handling Advice: Avoid freeze/thaw cycles.

Short Term Storage: -20°C

Long Term Storage: -80°C

Shipping: DRY ICE

Use & Stability:

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