anti-gamma-Synuclein, pAb

Product description: Polyclonal Antibody. Recognizes the Human protein. Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. Synuclein is a small, soluble protein primarily expressed in neural tissue. The synuclein family includes three known proteins: alpha-synuclein, beta-synuclein, and gamma-synuclein. gamma-Synuclein is a synuclein protein found primarily in the peripheral nervous system (in primary sensory neurons, sympathetic neurons, and motor neurons) and retina. gamma-Synuclein expression in breast tumors is a marker for tumor progression. Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway.

Alternate Names/Synonyms: SR; SNCG; BCSG1; Persyn; Synoretin; gamma-Synuclein; Breast Cancer-specific Gene 1 Protein

Product Type: Polyclonal Antibody

Immunogen: Recombinant human His-gamma Synuclein protein purified from E. coli.

Applications: WB

Species Crossreactivity: Human

Formulation: Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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Literature References: 1) Irvine GB et al. (2008) Mol Med. (General)2) Wakabayashi K et al. (2007) Neuropathology 27(5):494-506. (General)3) Beyer K. Acta Neuropathol 112(3):237-251. (General)4) Bruening W et al. (2000) Cancer 88(9):2154-2163. (General)