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10 µg

Ref. YIF-LF-P0278
AB FRONTIER

photos non contractuelles

Neuf 327.00 H.T.

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Détails Produit

Product Description: Human GM-CSF is a 24 kDa glycoprotein produced by a variety of cell types, including T and B lymphocytes, macrophages, keratinocytes, eosinophils, neutrophils, and endothelial cells in response to cytokine or inflammatory stimuli. GM-CSF was initially identified on the basis of its capacity to stimulate the clonal proliferation of myeloid precursors in vitro. GM-CSF promotes a Th1 biased immune response, allergic inflammation, and the development of autoimmunity. GM-CSF are particularly effective as antitumor vaccines. GM-CSF regulates multiple biological activities through activation of the GM-CSF receptor (GMCSFR), a member of the type I cytokine receptor group comprising a and b subunits.

Alternate Names/Synonyms: CSF; CSF2; GMCSF; GM-CSF; Molgramostin; Sargramostim; Colony-stimulating Factor; Granulocyte-macrophage Colony-stimulating Factor

Product type: Protein

Source / Host: E. coli

Species Crossreactivity: Human

Biological Activity: The ED50 for this effect is typically 10-40 pg/mL. Measured in a cell proliferation assay using the human growth factor-dependent cell line, TF-1.

Purity: >95% (SDS-PAGE)

Concentration: 0.5 mg/ml

Formulation: Liquid in PBS, 10% glycerol.

Handling Advice: Avoid freeze/thaw cycles.

Short Term Storage: -20°C

Long Term Storage: -80°C

Shipping: DRY ICE

Use & Stability:

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