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100 µl

Ref. YIF-LF-MA0335
AB Frontier

photos non contractuelles

Neuf 309.00 H.T.


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Détails Produit

Product description: Lactate dehydrogenase (LDH) is the enzyme in the glycolytic pathway that converts pyruvate to lactate with concomitant interconversion of NADH and NAD+. In mammals, the enzyme is encoded by three genes: LDHA (M or muscle form), LDHB (H or heart form), and LDHC (X or testis form). The three human LDHs have 84–89% sequence similarities and 69–75% amino acid identities. There are five different LDH isoenzymes based on the proportion of M and H chains existing in the LDH tetrameric structure. The LDHA is hypoxia inducible and its expression is directly controlled by the transcriptional activity of the hypoxia inducible factor 1alpha (HIF1alpha). LDHB is also known to be upregulated in many cancers.

Alternate Names/Synonyms: LDHB; LDH-B; LDH-H; EC=; LDH Heart Subunit; L-Lactate Dehydrogenase B Chain; Renal Carcinoma Antigen NY-REN-46

Product Type: Monoclonal Antibody

Clone: AF21F4

Isotype: Mouse IgG2b kappa

Immunogen: Recombinant human His-LDHB protein purified from E. coli.

Applications: ELISA, WB

Species Crossreactivity: Human, Mouse, Rat

Formulation: Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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