anti-Methionine Sulfoxide Reductase B, pAb

Product description: Polyclonal Antibody. Recognizes the Human, Mouse, Rat protein. Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. Methionine sulfoxide reductase B (MsrB), also known as SelX, is a selenoprotein. The oxidation of methionine at the sulfur atom leads to alternative epimers: R form of Met(O) and S form of Met(O). MsrB can reduce R form of both free and protein-incorporated methionine sulfoxide to methionine. It has a crucial role in protecting cells against oxidative damages. MsrA reduces only the S epimer of Met(O), and MsrB reduces the R epimer of Met(O) in proteins. Although the catalytic mechanisms of MsrA and MsrB are similar, two Msrs have no sequence identity and no structural similarity.

Alternate Names/Synonyms: SelR; SelX; Sepr; Msrb1; MsrB1; EC=1.8.4.-; Selenoprotein R; Selenoprotein X; Methionine-R-Sulfoxide Reductase B1

Product Type: Polyclonal Antibody

Immunogen: Recombinant mouse MSRB protein purified from E. coli.

Applications: WB

Species Crossreactivity: Human, Mouse, Rat

Concentration: 1 mg/ml

Formulation: Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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Literature References: 1) Zheung D. et al. (2003) J Biomol NMR. 27:183-184. (General)2) Weissbach H. (2002) Arch Biochem Biophys. 397:172-178. (General)3) Kryukov, G. (2002) Proc Natl Acad Sci USA. 99:4245-4250. (General)