Methionine Sulfoxide Reductase B SelCys95Cys (human) (rec.)

Product Description: Methionine sulfoxide reductase B (MsrB), also known as SelX, is a selenoprotein. The oxidation of methionine at the sulfur atom leads to alternative epimers: R form of Met(O) and S form of Met(O). MsrB can reduce R form of both free and protein-incorporated methionine sulfoxide to methionine. It has a crucial role in protecting cells against oxidative damages. MsrA reduces only the S epimer of Met(O), and MsrB reduces the R epimer of Met(O) in proteins. Although the catalytic mechanisms of MsrA and MsrB are similar, two Msrs have no sequence identity and no structural similarity.

Alternate Names/Synonyms: SelX; SEPX1; MsrB1; MSRB1; HSPC270; EC=1.8.4.-; Selenoprotein X; Methionine-R-Sulfoxide Reductase B1

Product type: Protein

Source / Host: E. coli

Species Crossreactivity: Human

Purity: >95% (SDS-PAGE)

Formulation: Lyophilized from 20mM HEPES, pH 7.4.

Handling Advice: Avoid freeze/thaw cycles.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: After reconstitution, store at -80°C.

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