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100 µl

Ref. YIF-LF-MA0356
AB FRONTIER

photos non contractuelles

Neuf 331.00 H.T.

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Détails Produit

Product description: Monoclonal Antibody. Recognizes the Human protein. Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. The N-myc gene belongs to a family of proto-oncogenes, including the highly related c-myc, N-myc, and L-myc genes, that encode transcription factors sharing many structural and biochemical functions . The structural motifs conserved between the MYC proteins include a basic helix-loop-helix domain and a leucine zipper domain involved in DNA-protein and protein-protein interactions, respectively. These motifs are also found in numerous transcription factors that control cell determination during diverse cell processes such as myogenesis, neurogenesis, and sex determination. May function as a transcription factor.

Alternate Names/Synonyms: MYCN; BHLHE37; bHLHe37; N-Nyc Proto-Oncogene Protein; Class E Basic Helix-Loop-Helix Protein 37

Product Type: Monoclonal Antibody

Clone: 6A4I

Isotype: Mouse IgG1 kappa

Immunogen: Synthetic peptide.

Applications: WB

Species Crossreactivity: Human

Formulation: Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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Literature References: 1) Potvin, E. Et al. (2010) Mol.Cell.Biol. 30:5348-5363. (General)2) Alt, F. Et al. (1986) Biol. 51:931-941. (General)3) Caudy, M. Et al. (1988) Cell 55:1061-1067. (General)4) Galderisi, U. Et al. (1999) J.Cell.Biochem. 73:97-105. (General)5) Malynn, B. Et al. (2000) Genes Dev. 14:1390-1399. (General)6) Olson, E. N. (1990) Genes Dev. 4:1454-1461. (General)7) Thisse, B. Et al. (1988) EMBO J. 7:2175-2183. (General)8) Villares, R. Et al. (1987) Cell 50:415-424. (General)