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1 Vial

Ref. REZ-1101021-1
REZOLVE SCIENTIFIC
1369583-75-4

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Neuf 307.00 H.T.

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Détails Produit

ReZolve-L1™ is a cell-permeant stain which has an affinity for polar lipids and can be used in a wide variety of live and fixed cells. This stain is an effective monitoring and tracer tool of cellular  lipid content (e.g. cholesterol, sphingolipid and phospholipid) and intracellular lipid localization and can be used to label lipid droplets and other high lipid-content compartments.

ReZolve-L1™ provides excellent photostablity and can be useful for a range of fluorescent applications, as it can be excited by UV and standard 405nm light sources. It is also computable with imaging by multiphoton microscopy and vibration spectroscopy techniques. Its large Stokes shift (ex/em 405/550nm) provides multiple options for dual and multicolour labelling applications. This cell permeable lipid stain has low cytotoxicity, which makes it ideally suited to live cell imaging, but can also be used for fixed biological samples. ReZolve-L1™ is easy to use with minimal sample preparation. This product has been used for monitoring lipids in live and fixed cell culture lines including murine cardiomyocytes (H9c2), murine adipocytes (3T3-L1) and human prostate cell lines (LNCaP, 22RV1, Du145 and PNT1a). Stain has been used on mammalian and insect tissues including sheep muscle and adipose tissue (live and fixed), murine brain and Drosophila larval gut and fatbody.

Key Attributes:

  • Simple and quick application

  • Suitable for fixed or live cell imaging

  • Low cytotoxicity

  • Highly resistant to photobleaching

  • Large stoke shift (Ex/Em 405 nm / 550 nm)

  • Compatible with other fluorescent dyes

  • Ideal for epi-fluorescence, confocal and multiphoton imaging

  • Infrared and Raman active

  • Stable at room temperature

Product Details
Product Type Chemical
Properties
Formula

C23H12N7O3Re

MW 620.6
CAS 1369583-75-4
Appearance Solid.
Solubility Soluble in DMSO.
Reconstitution Add 300µL of DMSO to obtain a 10mM stock solution. For working solution see protocol.
Declaration Manufactured by ReZolve Scientific.
Other Product Data

Click here for Original Manufacturer Product Data
Our product description may differ slightly from the original manufacturers product datasheet. For more information on applications please download the Preparation & Staining Protocol. The Expiry Date on the labels is based on storage at Room Temperature only.

InChi Key HKYHXALMIDNCEI-UHFFFAOYSA-N
Smiles O=[C][Re+]1(N2N=NC(C3=CC=C(C#N)C=C3)=N2)([N]4=CC=CC(C=C5)=C4C6=C5C=CC=[N]61)([C]=O)[C]=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage -20°C
Handling Advice Protect from light.
Protect from light when in solution.
Use/Stability Stable for at least 1 year after receipt when stored at +20°C.
Stable for at least 2 years after receipt when stored at -20°C.
Documents
Protocols Download PDF
Application Note Download PDF
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

 

Product References
  1. Modulation of the organelle specificity in Re(i) tetrazolato complexes leads to labeling of lipid droplets: C.A. Bader, et al.; RSC Advances 31, 16345 (2014)
  2. Unprecedented staining of polar lipids by a luminescent rhenium complex revealed by FTIR microspectroscopy in adipocytes: C.A. Bader, et al.; Mol. Biosyst. 12, 2064 (2016)
  3. A Molecular Probe for the Detection of Polar Lipids in Live Cells: C.A Bader, et al.; PLoS One 11, e0161557 (2016)
  4. Lipid profiles of prostate cancer cells: A. Sorvina, et al.; Oncotarget 9, 35541 (2018)
  5. Bright lights down under: Metal ion complexes turning the spotlight on metabolic processes at the cellular level: T.A. Gillam, et al.; Coord. Chem. Rev. 375, 234 (2018) (Review)