TRAIL (human) (rec.)

Product Description: In the field of cell biology, TNF-related apoptosis-inducing ligand (TRAIL), is a protein functioning as a ligand that induces the process of cell death called apoptosis. TRAIL is a cytokine that is produced and secreted by most normal tissue cells. It causes apoptosis primarily in tumor cells, by binding to certain death receptors. It has been used as a target of several anti-cancer therapeutics since the mid-1990s. These however have not shown significant survival benefit. TRAIL has also been designated CD253 (cluster of differentiation 253) and TNFSF10 (tumor necrosis factor (ligand) superfamily, member 10).

Alternate Names/Synonyms: TNF-related Apoptosis-inducing Ligand; CD253; TNFSF10

Product type: Protein

Source / Host: E. coli

Species Crossreactivity: Human

Biological Activity: 2-20ng/ml

Molecular Weight: 21kDa

Purity: >95% (SDS-PAGE)

Formulation: Lyophilized from 1x PBS, pH7.4.

Handling Advice: Avoid freeze/thaw cycles.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: After reconstitution, store at -80°C. Stable for at least 6 months after receipt when stored at -20°C.

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