Plus de 40 ans d’expérience à votre service

Tel. : 01 45 33 67 17 / E-mail : coger@coger.fr

Stock épuisé.
En rupture de stock
Quantité minimum d'achat
La quantité minimum d'achat n'est pas atteinte

 

 

20 µg

Ref. YIF-LF-P0079
AB FRONTIER

photos non contractuelles

Neuf 469.00 H.T.

Quantité

Alerte réapprovisionnement
Recevez une alerte par email dès que votre choix sera de retour en stock
Votre e-mail*:

Détails Produit

Product Description: Tumor necrosis factor-alpha (TNF-alpha) is a pleiotropic pro-inflammatory cytokine produced mainly by activated macrophages and in smaller amounts by several other types of cell. TNF-alpha has been isolated and characterized from a large number of mammals and fish species. TNF-alpha is expressed in two different forms: a soluble. Mature 17kDa form and a transmembrane 26kDa form. TNF-alpha interacts with two distinct cell-surface receptors, Tumor necrosis factor receptor 1 (TNFR1) and TNFR2. these mediate the cellular actions. The actions of TNF-alpha are diverse and profound involving inflammation, apoptosis, cell proliferation and the stimulation of various aspects within the immune system. TNF-alpha is increasingly recognized as a key regulator of lipid metabolism in adipose tissue and protein catabolism in muscle and in disease states such as cancer, Acquired Immune Deficiency Syndrome (AIDS) and obesity-related insulin resistance.

Alternate Names/Synonyms: TNF; TNFA

Product type: Protein

Source / Host: E. coli

Species Crossreactivity: Human

Biological Activity: The ED50 as determined by the cytolysis of murine L929 cells in the presense of actinomycin D is 0.03-0.06 ng/ml.

Purity: >98% (SDS-PAGE)

Formulation: Liquid in 20mM Tris, pH 8.0, 1mM EDTA, 10% Glycerol.

Handling Advice: Avoid freeze/thaw cycles.

Short Term Storage: -20°C

Long Term Storage: -80°C

Shipping: DRY ICE

Use & Stability: After reconstitution, store at -80°C.

Lien vers la Fiche Technique