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20 µg

Ref. YIF-LF-P0079
AB Frontier

photos non contractuelles

Neuf 437.00 H.T.


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Détails Produit

Product Description: Tumor necrosis factor-alpha (TNF-alpha) is a pleiotropic pro-inflammatory cytokine produced mainly by activated macrophages and in smaller amounts by several other types of cell. TNF-alpha has been isolated and characterized from a large number of mammals and fish species. TNF-alpha is expressed in two different forms: a soluble. Mature 17kDa form and a transmembrane 26kDa form. TNF-alpha interacts with two distinct cell-surface receptors, Tumor necrosis factor receptor 1 (TNFR1) and TNFR2. these mediate the cellular actions. The actions of TNF-alpha are diverse and profound involving inflammation, apoptosis, cell proliferation and the stimulation of various aspects within the immune system. TNF-alpha is increasingly recognized as a key regulator of lipid metabolism in adipose tissue and protein catabolism in muscle and in disease states such as cancer, Acquired Immune Deficiency Syndrome (AIDS) and obesity-related insulin resistance.

Alternate Names/Synonyms: TNF; TNFA

Product type: Protein

Source / Host: E. coli

Species Crossreactivity: Human

Purity: >95% (SDS-PAGE)

Formulation: Liquid in 20mM Tris, pH 8.0, 1mM EDTA, 10% Glycerol.

Handling Advice: Avoid freeze/thaw cycles.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: After reconstitution, store at -80°C.

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