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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Ubiquitin+1 (human) (rec.)
0.5 mg
photos non contractuelles
Détails Produit
Product Description: Ubiquitin+1 (Ub+1) is a novel mutant form of ubiquitin that can be produced through a process known as molecular frameshift. Ub+1 can be polyubiquitinated to produce aberrant polyubiquitin chains that inhibit the 26S proteasome. Especially ub+1 is accumulated in aggregates containing amyloid-beta and phosphorylated-tau. Elevated expression of Ub+1 mRNA and protein has been observed in the brains of patients with Alzheimer's disease. Also ub+1 acts as an aggravating factor in polyglutamine-induced neuro-degeneration.
Alternate Names/Synonyms: UBB; Frameshift
Product type: Protein
Source / Host: E. coli
Species Crossreactivity: Human
Purity: >95% (SDS-PAGE)
Concentration: 1 mg/ml
Formulation: Liquid in 20mM HEPES, pH7.0, 10% Glycerol.
Handling Advice: Avoid freeze/thaw cycles.
Short Term Storage: -20°C
Long Term Storage: -80°C
Shipping: DRY ICE
Use & Stability:
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