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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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10Z-Hymenialdisine
1 mg
photos non contractuelles
Détails Produit
Product description: Chemical. CAS: 82005-12-7. Formula: C11H10BrN5O2. MW: 324.1. Isolated from sponge Axinella carteri. Insecticidal and cytotoxic. Potent NF-kappaB inhibitor. Inhibits various pro-inflammatory cytokines such as IL-1, IL-2, IL-6, IL-8, TNF-alpha and nitric oxide (NO) in a variety of cell lines. ATP-competitive kinase inhibitor. Inhibits DNA damage checkpoint at G2, cyclin-dependent kinases CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, CDK5/p25, GSK-3beta and casein kinase 1 (CK1). Potent mitogen-activated protein kinase kinase-1 (MEK-1) inhibitor. MARK (microtubule affinity-regulating kinase) inhibitor.
Alternate Names/Synonyms: Hymenialdisine; 4-(2-Amino-4-oxo-2-imidazolidin-5-ylidene)-2-bromo-4,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8-one
Product Type: Chemical
Molecular Formula: C11H10BrN5O2
Molecular Weight: 324.1
CAS: 82005-12-7
Source / Host: Isolated from sponge Axinella carteri.
Purity: >97% (HPLC) (Contains traces of the 10E-isomer)
InChiKey: ATBAETXFFCOZOY-DAXSKMNVSA-N
Appearance: Yellow oil.
Solubility: Soluble in DMSO.
Short Term Storage: +4°C
Long Term Storage: -20°C
Long Shipping: AMBIENT
Use & Stability: Stable for at least 2 years after receipt when stored at -20°C.
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