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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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7-Azido-4-methylcoumarin
50 mg
photos non contractuelles
Détails Produit
Product description: Chemical. CAS: 95633-27-5. Formula: C10H7N3O2. MW: 201.18. Synthetic 7-Azido-4-methylcoumarin is a highly sensitive and selective fluorogenic H2S probe. The aromatic azide moiety of AzMC is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with lambdaex = 365 nm and lambdaem = 450 nm. It is a photoaffinity labeling probe for the substrate binding site of human sulfotransferase 1A1 (SULT1A1). 7-Azido-4-methylcoumarin is a tool for monitoring the activity of pyridoxal-5'-phosphate (PLP)-dependent enzymes (e.g. cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CGL) and tryptophan synthase (TS)) and to identify novel cystathionine beta-synthase (CBS) inhibitors and activators.
Alternate Names/Synonyms: 7-Azido-4-methyl-1-benzopyran-2-one; AzMC
Product Type: Chemical
Molecular Formula: C10H7N3O2
Molecular Weight: 201.18
CAS: 95633-27-5
Source / Host: Synthetic
Purity: >98% (HPLC)
InChiKey: HEKDKVLIMUWRRZ-UHFFFAOYSA-N
Appearance: Yellow powder.
Solubility: Soluble in DMSO.
Short Term Storage: +4°C
Long Term Storage: -20°C
Long Shipping: AMBIENT
Use & Stability: Stable for at least 2 years after receipt when stored at -20°C.
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