7-Azido-4-methylcoumarin

Product description: Chemical. CAS: 95633-27-5. Formula: C10H7N3O2. MW: 201.18. Synthetic 7-Azido-4-methylcoumarin is a highly sensitive and selective fluorogenic H2S probe. The aromatic azide moiety of AzMC is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with lambdaex = 365 nm and lambdaem = 450 nm. It is a photoaffinity labeling probe for the substrate binding site of human sulfotransferase 1A1 (SULT1A1). 7-Azido-4-methylcoumarin is a tool for monitoring the activity of pyridoxal-5'-phosphate (PLP)-dependent enzymes (e.g. cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CGL) and tryptophan synthase (TS)) and to identify novel cystathionine beta-synthase (CBS) inhibitors and activators.

Alternate Names/Synonyms: 7-Azido-4-methyl-1-benzopyran-2-one; AzMC

Product Type: Chemical

Molecular Formula: C10H7N3O2

Molecular Weight: 201.18

CAS: 95633-27-5

Source / Host: Synthetic

Purity: >98% (HPLC)

InChiKey: HEKDKVLIMUWRRZ-UHFFFAOYSA-N

Appearance: Yellow powder.

Solubility: Soluble in DMSO.

Short Term Storage: +4°C

Long Term Storage: -20°C

Long Shipping: AMBIENT

Use & Stability: Stable for at least 2 years after receipt when stored at -20°C.

Lien vers la Fiche Technique