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Product description: Aniso-Actinomycin (4-Oxopro instead of Pro in the beta-chain). Antitumor and antiviral antibiotic. Antituberculosis agent. Has higher cytotoxicity towards cultured human leukemia (HL-60) cells than actinomycin D. Apoptosis inducer. Forms a complex with DNA and blocks its biological activity.
Alternate Names/Synonyms: Actinomycin A5; Actinomycin B2; Actinomycin V; Actinomycin D, 3A-(4-oxo-L-proline); NSC175006
Product Type: Chemical
Molecular Formula: C62H84N12O17
Molecular Weight: 1269.4
CAS: 18865-48-0
Source / Host: Isolated from Streptomyces sp.
Purity: >98% (HPLC)
InChiKey: SMBASHZPOHFQRU-ILYIJYFNSA-N
Appearance Orange crystals.
Solubility: Soluble in DMSO, methanol, acetone or chloroform.
Short Term Storage: +4°C
Long Term Storage: -20°C
Shipping: AMBIENT
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.
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