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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Agelasine D
1 mg
photos non contractuelles
Détails Produit
Product description: Chemical. CAS: 92664-80-7. Formula: C26H40N5. MW: 422.6. Isolated from sponge Agelas sp. Antifouling compound. Antimycobacterial and antibacterial agent. Exerts its antibacterial effect by inhibiting enzyme BCG 3185c, a suspected dioxygenase thereby disrupting bacterial homeostasis. Associated with contractive responses of smooth muscles and inhibition of Na+/K+ ATPase. Cytotoxic/Antineoplastic agent. Found to exhibit inhibitory activity against several cancer cell lines, including the drug resistant renal cancer cell line (ACHN). Suppressor of RANKL-induced osteoclastogenesis via down-regulation of c-Fos, NFATc1, NF-kappaB and ERK. Antiprotozoal compound.
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