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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Product description: Chemical. CAS: 5508-58-7. Formula: C20H30O5. MW: 350.455. Andrographolide, a bioactive diterpene lactone, is the main constituent of Andrographis paniculata, a plant used in traditional medicines. It is known to have different biological properties such as anti-inflammatory, immunosuppressive, antidiabetic, antihyperglycemic, antibacterial, antioxidant, antinoniceptive, antimalarial, anticancer and hepatoprotective activity. It also shows potent anti-viral effect against dengue virus. It blocks T-cell proliferation and the proliferation of several cancer cell lines in vitro. It acts as an irreversible antagonist of NF-kappa and AP-1 (IC50 < 15 µM) activation, and prevents in vitro and in vivo T cell activation.
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