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30 µg

Ref. JAI-MHH-030N
JAICA

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Neuf 828.00 H.T.
en stock

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Détails Produit

Product description: Monoclonal Antibody. Recognizes HHE-modified proteins (especially HHE-His Michael adducts). Frozen liquid. Contains 10mM PBS, 0.1% NaN3 and 0.5% BSA. 4-hydroxy-2-alkenal is one of the major lipid peroxidation products, and shows many biological effects such as high toxicity to cells. Among them, 4-hydroxy-2-hexenal (HHE) is an aldehyde formed during peroxidation of n-3 fatty acids such as docosahexaenoic acid. HHE is highly reactive aldehyde and reacts with histidine residue of protein to form Michael-addition type adducts.

Alternate Names/Synonyms:

Product Type: Monoclonal Antibody

Clone: HHE53

Isotype: Mouse IgG1kappa

Immunogen: HHE-modified keyhole-lympet hemocyanine.

Applications: IHC

Species Crossreactivity: All, Human

Specificity: Recognizes HHE-modified proteins (especially HHE-His Michael adducts).

Formulation: Frozen liquid. Contains 10mM PBS, 0.1% NaN3 and 0.5% BSA.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 3 years after receipt when stored at -20°C.

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Literature References: Protein-bound 4-hydroxy-2-hexenal as a marker of oxidized n-3 polyunsaturated fatty acids: S. Yamada, et al.; J. Lipid. Res. 45, 626 (2004) | Accumulation of protein-bound 4-hydroxy-2-hexenal in spinal cords from patients with sporadic amyotrophic lateralsclerosis: N. Shibata, et al.; Brain Res. 1019, 170 (2004)