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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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anti-5-Formylcytosines (5-fC), Rabbit Monoclonal (RM477)
50 µg
photos non contractuelles
Détails Produit
Product description: Recombinant Antibody. RM477 reacts to 5-Formylcytosine (5-fC) in DNA. No cross-reactivity with non-modified cytosine and other modified cytosines in DNA. Isotype: Rabbit IgG. Immunogen: KLH-conjugated 5-Formylcytosine. Applications: ELISA, DotBlot. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. 5-Formylcytosine (5fC) is a pyrimidine nitrogen base derived from cytosine and a recently discovered modification of DNA. Just as 5-hydroxymethylcytosine (5-hmC) is generated when the Tet family of cytosine oxygenase enzymes converts 5-methylcytosine (5-mC), it has been shown that continued activity of the Tet proteins on hydroxymethylcytosine will generate 5-formylcytosine (5-fC) and 5-carboxylcytosine. It is believed that this conversion process may represent a pathway of DNA demethylation.
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