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50 µg

Ref. AG-20A-0001-C050
ADIPOGEN LIFE SCIENCES

photos non contractuelles

Neuf 170.00 H.T.
en stock

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Détails Produit

Product description: Monoclonal Antibody. Recognizes human adiponectin. Detects a band of ~30kDa by Western blot. Cross-reactivity with other species not tested. Isotype: Mouse IgG1kappa. Clone: HADI 773. Applications: ELISA, IHC, WB. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. ACRP30 was identified as a novel adipocyte-specific synthesized and secreted protein with structural resemblance to complement factor C1q. Like adipsin, ACRP30 secretion is induced ~10-fold during adipocyte differentiation. Plasma levels are reduced in obese humans, and low levels are associated with insulin-resistance. Treatment of db/db mice with TZD increased ACRP30 levels.

Alternate Names/Synonyms: ACRP30; AdipoQ; apM1; GBP28; Adipocyte Complement Related Protein of 30kDa

Product Type: Monoclonal Antibody

Clone: HADI 773

Isotype: Mouse IgG1kappa

Immunogen: Recombinant human adiponectin.

Applications: ELISA, IHC, WB

Species Crossreactivity: Human

Specificity: Recognizes human adiponectin. Detects a band of ~30kDa by Western blot. Cross-reactivity with other species not tested.

Concentration: 1mg/ml

Formulation: Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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Literature References: Plasma resistin concentrations measured by enzyme-linked immunosorbent assay using a newly developed monoclonal antibody are elevated in individuals with type 2 diabetes mellitus: B.S. Youn, et al.; J. Clin. Endocrinol. Metab. 89, 150 (2004) | Genetic association study of adiponectin polymorphisms with risk of Type 2 diabetes mellitus in Korean population: Y.Y. Lee, et al.; Diabet. Med. 22, 569 (2005) | Adiponectin expression in human fetal tissues during mid- and late gestation: S. Corbetta, et al,; J. Clin. Endocrinol. Metab. 90, 2397(2005) | Renin receptor expression in human adipose tissue: V. Achard, et al.; Am. J. Physiol. Regul. Integr. Comp. Physiol. 292, R274 (2007) | Adiponectin immunohistochemical expression in colorectal cancer and its correlation with histological grade and tumour microvessel density: V. Barresi, et al.; Pathology 41, 533 (2009) | The expression of adiponectin receptors Adipo-R1 and Adipo-R2 is associated with an intestinal histotype and longer survival in gastric carcinoma: V. Barresi, et al.; J. Clin. Pathol. 62, 705 (2009)