anti-BAFF (mouse), mAb (blocking) (Sandy-2) (preservative free)

Product description: BAFF is a master regulator of peripheral B cell survival and, together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren’s syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).

Alternate Names/Synonyms: BLyS; TALL-1; CD257; B Cell Activating Factor; TNFSF13B

Product Type: Monoclonal Antibody

Clone: Sandy-2

Isotype: Mouse IgG1

Immunogen: Recombinant mouse BAFF.

Labels - Conjugates: Preservative Free

Applications: FUNC (Blocking), IP

Species Crossreactivity: Mouse

Specificity: Recognizes mouse BAFF.

Endotoxin: <0.01EU/µg purified protein (LAL test; Lonza).

Concentration: 1mg/ml

Formulation: Liquid. In PBS containing 10% glycerol.

Long Term Storage: +4°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at +4°C.

Lien vers la Fiche Technique