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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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anti-beta-Tubulin, mAb (AXO45)
100 µg
photos non contractuelles
Détails Produit
Product description: Monoclonal Antibody. Detects almost all isotypes of ?-tubulin specifically in cells and tissues of mouse, human and ciliates. Applications: ICC, IHC, IP and WB. Clone: AXO45. Isotype: Mouse IgG1. The ?-tubulin monoclonal antibody (AXO45) was developed by isolating the cilia from unicellular multiciliated Paramecium and purifying the core microtubule-based structures of the cilia, the axonemes. These axonemes were electrophoresed on a SDS-PAGE and the tubulin band was used as an antigen to develop monoclonal antibodies targeting both ?- and ?-tubulin (A.M. Callen, et al.; 1994). The antibody AXO45 recognizes the C-terminal region between residues 257 and 442 of ?-tubulin. Although the antibody was raised against the ?-tubulin found in cilia, it is able to recognize ?-tubulin of all microtubule networks, indicating that it can potentially recognize different isotypes of ?-tubulin found in mammals.
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