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100 µg

Ref. AG-20B-0042B-C100
AdipoGen Life Sciences

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Neuf 400.00 H.T.

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Détails Produit

Product description: Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.

Alternate Names/Synonyms: Interleukin-1beta Convertase; IL-1BC; Interleukin-1beta-converting Enzyme; ICE;

Product Type: Monoclonal Antibody

Clone: Casper-1

Isotype: Mouse IgG1

Immunogen: Recombinant mouse caspase-1.

Labels - Conjugates: Biotin

Applications: IHC, IP, WB

Species Crossreactivity: Mouse

Specificity: Recognizes endogenous full-length and activated (p20 fragment) mouse caspase-1.

Concentration: 0.5mg/ml

Formulation: Liquid. In PBS containing 0.02% sodium azide.

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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