anti-CD257 [BAFF] (human), mAb (ANC2H3) (preservative free)

Product description: BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren’s syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).

Alternate Names/Synonyms: BAFF; Blys; TALL-1; B Cell Activating Factor; Tumor Necrosis Factor Ligand Superfamily Member 13B; TNFSF13B

Product Type: Monoclonal Antibody

Clone: ANC2H3

Isotype: Mouse IgG1kappa

Immunogen: Recombinant soluble human CD257(BAFF).

Labels - Conjugates: Preservative Free

Applications: ELISA, FACS, FUNC (Blocking)

Species Crossreactivity: Human

Short Term Storage: +4°C

Long Term Storage: +4°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at +4°C.

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