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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Product description: The inflammatory actions of IL-1alpha and beta depend on their interaction with its receptor, IL-1R1, and can be negatively controlled by several inhibitors such as IL-1Ra, IL-1R type 2 (IL-1R2), SIGIRR and the soluble form of IL-1 receptor accessory protein (IL-1RAcP). IL-1R2 neutralizes IL-1 either as a surface decoy receptor or in a cleaved and secreted form. IL-1R2 is expressed on B cells, on neutrophils and on in vitro expanded human Tregs.
Alternate Names/Synonyms: CD121 Antigen-like Family Member B; IL-1 Type II Receptor; Interleukin-1 Receptor beta Interleukin-1 Receptor Type II; CD121b
Product Type: Recombinant Antibody
Clone: Praxy-1-1
Isotype: Mouse IgG2blambda
Immunogen: Recombinant mouse IL-1R2 (extracellular domain).
Applications: ELISA, FACS
Species Crossreactivity: Mouse
Specificity: Recognizes mouse IL-1R2.
Endotoxin: <0.01EU/µg purified protein (LAL-test; Lonza).
Concentration: 1mg/ml.
Formulation: Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Long Term Storage: -20°C
Shipping: BLUE ICE
Use & Stability: Stable for at least 1 month after receipt when stored at +4°C. Stable for at least 1 year after receipt when stored at -20°C.
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