anti-IL-1R2 (mouse), mAb (rec.) (blocking) (Praxy-1-1)

Product description: The inflammatory actions of IL-1alpha and beta depend on their interaction with its receptor, IL-1R1, and can be negatively controlled by several inhibitors such as IL-1Ra, IL-1R type 2 (IL-1R2), SIGIRR and the soluble form of IL-1 receptor accessory protein (IL-1RAcP). IL-1R2 neutralizes IL-1 either as a surface decoy receptor or in a cleaved and secreted form. IL-1R2 is expressed on B cells, on neutrophils and on in vitro expanded human Tregs.

Alternate Names/Synonyms: CD121 Antigen-like Family Member B; IL-1 Type II Receptor; Interleukin-1 Receptor beta Interleukin-1 Receptor Type II; CD121b

Product Type: Recombinant Antibody

Clone: Praxy-1-1

Isotype: Mouse IgG2blambda

Immunogen: Recombinant mouse IL-1R2 (extracellular domain).

Applications: ELISA, FACS

Species Crossreactivity: Mouse

Specificity: Recognizes mouse IL-1R2.

Endotoxin: <0.01EU/µg purified protein (LAL-test; Lonza).

Concentration: 1mg/ml.

Formulation: Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 month after receipt when stored at +4°C. Stable for at least 1 year after receipt when stored at -20°C.

Lien vers la Fiche Technique