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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Product description: Reactive nitrogen species (RNS) are formed in a variety of diseases such as atherosclerosis, inflammation, cancer and neurodegenerative diseases. Peroxinitrite (ONOO-) is known as a potent biological oxidant, which is formed via very fast reaction between nitric oxide (NO) and superoxide (O2-). Peroxinitrite can induce nitration of aromatic amino acids such as Tyr, Trp, Phe and His, which results in modulation of protein functions. To date, 6-nitrotryptophan (6-NO2-Trp) is shown to be one of the most stable and major peroxynitrite-modified amino acids, and growing evidences suggest that nitrotryptophan may play a significant role in the cellular regulation under nitrosative stress. This antibody is suitable for immunohistochemistry, western blotting and ELISA and may provide a powerful tool for the investigation of nitrosative stress inside living bodies.
Product Type: Monoclonal Antibody
Clone: 117C
Isotype: Mouse IgG1kappa
Immunogen: 6-Nitrotryptophan modified Keyhole Limpet Hemocyanin (KLH).
Applications: IHC, WB
Species Crossreactivity: All, Human
Specificity: Recognizes 6-Nitrotryptophan.
Concentration: 100µg/ml of IgG in 10mM PBS (pH 7.4).
Formulation: Lyophilized.
Long Term Storage: -20°C
Shipping: BLUE ICE
Use & Stability: Stable for at least 3 years after receipt when stored at -20°C.
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