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100 µg

Ref. AG-20B-0052-C100
AdipoGen Life Sciences

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Neuf 290.00 H.T.

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Détails Produit

Product description: Monoclonal Antibody. Recognizes human and mouse endogenous Notch-2 receptor. Isotype: Rat IgG1kappa. Clone: 16F11. Applications: FACS. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.

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