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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Product description: Recombinant Antibody. This antibody reacts to human TIM3 (Hepatitis A virus cellular receptor 2). Applications: IHC, WB. Clone: RM448. Isotype: Rabbit IgG. Formulation: Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. T cell Immunoglobulin and Mucin Domain-containing Molecule-3 (TIM-3) is present on T-helper type 1 lymphocytes and other immune cells including dendritic cells and natural killer cells. TIM-3 is overexpressed in CD4+ tumor-infiltrating lymphocytes, including those with non-small cell lung cancer associated with poor prognoses. The TIM gene family has an important role in the regulation of autoimmunity and allergies. TIM-3 has recently emerged as a potential target for cancer immunotherapy.
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