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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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(+)-Aphidicolin
1 mg
photos non contractuelles
Détails Produit
Product description: Phytotoxin. Antibiotic. Antiviral and antineoplastic agent. Antileishmanial agent. Reversible inhibitor of eukaryotic nuclear DNA replication. Useful for cell synchronization. Blocks the cell cycle at G1/S phase. Prolongs the half life of DNA methyltransferase. DNA methylation/demethylation modulator. Specific DNA polymerase alpha and delta inhibitor in eukaryotic cells and in some viruses of animal origin. Acts synergistically with vincristine and doxorubicin. Apoptosis inhibitor/inducer.
Alternate Names/Synonyms: NSC234714; BRN4689958; ICI69653
Product Type: Chemical
Molecular Formula: C20H34O4
Molecular Weight: 338.5
CAS: 38966-21-1
Source / Host: Isolated from Phoma sp. BS 7210.
Purity: >98% (HPLC)
InChiKey: NOFOAYPPHIUXJR-APNQCZIXSA-N
Appearance White to off-white solid.
Solubility: Soluble in DMSO (50 mg/ml), methanol (10 mg/ml) or 100% ethanol; insoluble in water.
Short Term Storage: +4°C
Long Term Storage: +4°C
Shipping: AMBIENT
Use & Stability: Stable for at least 1 year after receipt when stored at +4°C. After reconstitution protect from light at -20°C.
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