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5 mg

Ref. SYN-1011-M005

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Neuf 210.00 H.T.


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Détails Produit

Product description: Aurora kinases play a key role in the regulation of mitosis and in recent years have become attractive targets for the treatment of cancer. AT9283 is a powerful inhibitor of Aurora A and B kinases as well as several other important kinases including JAK2 and Abl (T315I). AT9283 has also been shown effective in mouise xenograft models and has been studied as a possible clinical candidate. Effective IC(50) doses for Aurora kinases are in the low 2-3nM range, and inhibition of a number of other kinases including JAK2 has been reported at 1-10nM.

Alternate Names/Synonyms: AT-9283

Product Type: Chemical

Molecular Formula: C19H23N7O2

Molecular Weight: 381.4

CAS: 896466-04-9

Purity: >95%


Appearance Solid.

Solubility: Soluble in DMSO or ethanol.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: AMBIENT

Use & Stability: Stable for at least 2 years after receipt when stored at -20°C.

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