Coger: Distributeur de reactifs de laboratoire
AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
|
Ajouter au panier
Le produit a été ajouté au panier Le stock est insuffisant. unités ont été rajoutées au panier Total:
|
|
Stock épuisé.
En rupture de stock
|
|
Quantité minimum d'achat
La quantité minimum d'achat n'est pas atteinte
|
AZD1208
100 mg
photos non contractuelles
Détails Produit
Product description: Potent, highly selective and orally available Pim kinase inhibitor that effectively inhibits all three isoforms Pim-1, Pim-2 and Pim-3 at <5nM or <150 nM in enzyme and cell assays, respectively. Potently inhibits colony growth and Pim signalling substrates in primary AML cells from bone marrow that are Flt3 wild-type or Flt3 internal tandem duplication mutants. Upregulation of Pim kinases is observed in several types of leukemias and lymphomas. Pim-1, -2 and -3 promote cell proliferation and survival downstream of cytokine and growth factor signaling pathways.
Alternate Names/Synonyms: AZD-1208
Product Type: Chemical
Molecular Formula: C21H21N3O2S
Molecular Weight: 379.5
CAS: 1204144-28-4
Purity: >95%
InChiKey: MCUJKPPARUPFJM-UWCCDQBKSA-N
Appearance Solid.
Solubility: Soluble in DMSO.
Short Term Storage: +4°C
Long Term Storage: -20°C
Shipping: AMBIENT
Use & Stability: Stable for at least 2 years after receipt when stored at -20°C.
|
Alerte
Veuillez saisir les champs obligatoires! |
