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5 mg

Ref. SYN-1160-M005
SynKinase
1357158-81-6

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Neuf 461.00 H.T.

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Détails Produit

Product description: AZD-26 is an inhibitor of AKT. AZD-26 inhibits the phosphorylation of Thr308 on AKT in BT474 cells with an IC(50) of 422nM. It also inhibits the phosphorylation of Ser473 on AKT in MDAMB468 cells with an IC(50) of 322nM. AZD-26 inhibited AKT mediated phosphorylation at ranges form 0.01µM to 10µM after 24 hour exposure in several rat and human cell models. Likewise AZD-25 used at 100-200mg/kg also inhibited AKT phosphorylation and subsequent activation.

Alternate Names/Synonyms: AZD26

Product Type: Chemical

Molecular Formula: C22H21N3O

Molecular Weight: 343.4

CAS: 1357158-81-6

Purity: >95%

InChiKey: GIRZDHCBMNHMEH-UHFFFAOYSA-N

Appearance Solid.

Solubility: Soluble in DMSO or ethanol.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: AMBIENT

Use & Stability: Stable for at least 2 years after receipt when stored at -20°C.

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