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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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AZD-26
10 mg
photos non contractuelles
Détails Produit
Product description: AZD-26 is an inhibitor of AKT. AZD-26 inhibits the phosphorylation of Thr308 on AKT in BT474 cells with an IC(50) of 422nM. It also inhibits the phosphorylation of Ser473 on AKT in MDAMB468 cells with an IC(50) of 322nM. AZD-26 inhibited AKT mediated phosphorylation at ranges form 0.01µM to 10µM after 24 hour exposure in several rat and human cell models. Likewise AZD-25 used at 100-200mg/kg also inhibited AKT phosphorylation and subsequent activation.
Alternate Names/Synonyms: AZD26
Product Type: Chemical
Molecular Formula: C22H21N3O
Molecular Weight: 343.4
CAS: 1357158-81-6
Purity: >95%
InChiKey: GIRZDHCBMNHMEH-UHFFFAOYSA-N
Appearance Solid.
Solubility: Soluble in DMSO or ethanol.
Short Term Storage: +4°C
Long Term Storage: -20°C
Shipping: AMBIENT
Use & Stability: Stable for at least 2 years after receipt when stored at -20°C.
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