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100 µg

Ref. CHI-HF-211B7H3B-C100

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Neuf 350.00 H.T.


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Détails Produit

Product Description: B7-H3(4Ig) or B7-H3b has two additional Ig-like domains (one V- type and one C- type) and shows a ubiquituous expression pattern. B7-H3(4Ig) is expressed on dendritic cells as well as activated T, B and NK cells. Human (4Ig) binding to an undefined receptor has shown to be inhibitory to NK cell illing and cytokine release. It also seems to be required for late stage osteoblast differentiation.

Product type: Protein

Source / Host: HEK 293 cells

Sequence: The extracellular domain of human B7-H3(4Ig) [B7-H3b] (aa 27-461) is fused to the N-terminus of the Fc region of mouse IgG2a.

Species Crossreactivity: Human

Biological Activity: Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated human T cells.

Molecular Weight: ~100kDa (SDS-PAGE)

TAGs: Fc

Purity: >98% (SDS-PAGE)

Endotoxin: <5EU/mg protein (LAL test; Lonza).

Formulation: Lyophilized from 0.2µm-filtered solution in PBS.

Handling Advice: Avoid freeze/thaw cycles.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

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