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5 mg

Ref. BVT-0098-M005

photos non contractuelles

Neuf 390.00 H.T.
en stock


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Détails Produit

Product description: Macrolide antibiotic. Bacterial, protozoan and mammalian threonyl-tRNA synthetase (THrRS) inhibitor. Antiangiogenic (IC50 = 0.8 nM) and anticancer agent. Induces the collapse of formed capillary tubes in a dose-dependent fashion. In HUVECs, the capillary tube collapsing activity is mediated by the activation of caspases-3 and -8 and induction of apoptosis. Blocks the formation of spontaneous lung metastases of B16-BL6 melanoma cells. Cyclin-dependent kinase (CDK) inhibitor. Antiviral. Potent antimalarial agent (IC50 = 0.97 nM). Inhibitor of potato scab disease.

Product Type: Chemical

Molecular Formula: C28H43NO6

Molecular Weight: 489.6

CAS: 7184-60-3

Source/Host Chemicals: Isolated from Streptomyces sp.

Purity: >98% (HPLC)


Appearance: White to off-white powder.

Solubility: Soluble in DMSO or methanol.

Short Term Storage: +4°C

Long Term Storage: -20°C

Long Shipping: AMBIENT

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.

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