CCL22 (human):Fc (human) (rec.)

Product Description: CCL22, also named stimulated T cell chemotactic protein (STCP1), is a CC chemokine initially isolated from clones of monocyte-derived macrophages and binds to the receptor CCR4. Human CCL22 is highly expressed in macrophage and in monocyte-derived dendritic cells and thymus. It is also found in lymph node, appendix, activated monocytes, resting and activated macrophages. May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. CCL22 has been shown to induce chemotaxis or Ca2+ mobilization in dendritic cells, IL-2 activated NK cells and activated T lymphocytes.

Alternate Names/Synonyms: C-C Motif Chemokine 22; CC Chemokine STCP-1; Stimulated T Cell Chemotactic Protein 1; MDC; Macrophage-derived Chemokine; Small-inducible Cytokine A22

Product type: Protein

Source / Host: CHO cells

Sequence: The extracellular domain of human CCL22 (aa 25-93) is fused to the N-terminus of the Fc region of human IgG1.

Species Crossreactivity: Human

TAGs: Fc

Purity: >98% (SDS-PAGE)

Endotoxin: <0.06EU/µg protein (LAL test; Lonza).

Formulation: Lyophilized from 0.2µm-filtered solution in PBS.

Handling Advice: Avoid freeze/thaw cycles.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

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