CCL24 (human):Fc (human) (rec.)

Product Description: CCL24 (eotaxin-2) has been shown to induce chemotaxis of eosinophils, basophils and resting T lymphocytes but not monocytes and activated T lymphocytes. CCL24 is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. CCL24 interacts with chemokine receptor CCR3 to induce chemotaxis in eosinophils. Elevated levels of CCL24 has been seen in patients with aspirin-exacerbated respiratory disease (AERD), such as asthma.

Alternate Names/Synonyms: Eotaxin-2; C-C Motif Chemokine 24; Eosinophil Chemotactic Protein 2; Myeloid Progenitor Inhibitory Factor 2; MPIF-2; Small-inducible Cytokine A24; CKbeta6

Product type: Protein

Source / Host: CHO cells

Sequence: The extracellular domain of human CCL24 (aa 27-119) is fused to the N-terminus of the Fc region of human IgG1.

Species Crossreactivity: Human

TAGs: Fc

Purity: >98% (SDS-PAGE)

Endotoxin: <0.06EU/µg protein (LAL test; Lonza).

Formulation: Lyophilized from 0.2µm-filtered solution in PBS.

Handling Advice: Avoid freeze/thaw cycles.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

Lien vers la Fiche Technique