Coger: Distributeur de reactifs de laboratoire
AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
|
Ajouter au panier
Le produit a été ajouté au panier Le stock est insuffisant. unités ont été rajoutées au panier Total:
|
|
Stock épuisé.
En rupture de stock
|
|
Quantité minimum d'achat
La quantité minimum d'achat n'est pas atteinte
|
Collinolactone
250 µg
photos non contractuelles
Détails Produit
Product description: Chemical. CAS: 2733581-46-7. Formula: C21H28O5. MW: 360.45. Collinolactone has neuroprotective and anti-neurodegenerative effects by reducing intracellular oxidative stress. It protects against glutamate-induced oxidative stress in a dose-dependent manner. Collinolactone is a potential anti-Alzheimer agent with A?-disaggregating activity. It showed dissociative effect on A? aggregates and tau tangles in vitro, with significantly reduced apoptosis and inflammation in neuronal and glial cells. In vivo studies on APP/PS1 double transgenic mice showed substantially dissociated hippocampal plaques. A set of semisynthetic collinolactone analogs (but not collinolactone) has shown inhibitory effects on a L929 cell line.
|
Alerte
Veuillez saisir les champs obligatoires! |
