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25 µg

Ref. BVT-0237-C025

photos non contractuelles

Neuf 75.00 H.T.


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Détails Produit

Product description: Antibiotic. More potent and specific H+-ATPase inhibitor than bafilomycin A1 (Prod. No. BVT-0252). Inhibits acidification of organelles such as lysosomes and the Golgi apparatus. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Blocks cell surface expression of viral glycoproteins without affecting their synthesis. Cytotoxic in a number of cell lines in a cell viability assay. Induces nitric oxide (NO) production.

Alternate Names/Synonyms: Folimycin; Antibiotic TAN 1323B; Antibiotic X4357B

Product Type: Chemical

Molecular Formula: C46H75NO14

Molecular Weight: 866.1

CAS: 80890-47-7

Source / Host: Isolated from Streptomyces sp.

Purity: >98% (HPLC)


Appearance White to off-white solid.

Solubility: Soluble in methanol, DMSO or acetonitrile; insoluble in water.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: AMBIENT

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.

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