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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Product description: Chemical. CAS: 81552-33-2. Formula: C45H73NO14. MW: 852.1. Isolated from Streptomyces sp. Antibiotic. Exhibits similar activity as concanamycin A (Prod. No. BVT-0237) and concanamycin C (Prod. No. BVT-0254). Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Suppresses bone resorption. Inhibits proliferation of mouse splenic lymphocytes. Antifungal and larvicidal.
Alternate Names/Synonyms: 8-Deethyl-8-methylconcanamycin A
Product Type: Chemical
Molecular Formula: C45H73NO14
Molecular Weight: 852.1
CAS: 81552-33-2
Source / Host: Isolated from Streptomyces sp.
Purity: >98% (HPLC)
InChiKey: AQXXGIBOZQZSAT-UZYXLCJWSA-N
Appearance: White to off-white solid.
Solubility: Soluble in DMSO, chloroform, acetonitrile or methanol; insoluble in water.
Short Term Storage: +4°C
Long Term Storage: -20°C
Long Shipping: AMBIENT
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
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