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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Cordycepin
10 mg
photos non contractuelles
Détails Produit
Product description: Chemical. CAS: 73-03-0. Formula: C10H13N5O3. MW: 251.24. Synthetic. Cordycepin is a nucleoside (adenosine analog) antibiotic that acts as a polyadenylation inhibitor when converted to 3-deoxyadenosine triphosphate (3'-dATP), which inhibits ATP-dependent DNA and RNA synthesis. Cordycepin has a broad spectrum of biological activities, including anticancer, anti-proliferative, pro-apoptotic, anti-inflammatory and antifungal effects. It was shown to modulate autophagy and NLRP3 inflammasome. Cordycepin has been shown to reduce poly(A) tail length in mRNA, to activate AMPK kinase, leading to a reduction in mTOR signalling, downregulate ERK/Akt/PI3K/GSK-3beta/beta-catenin signaling pathways. Also useful for the study of messenger RNA transcription.
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