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1 Ea

Ref. 610023-1Ea
AVANTI POLAR LIPIDS

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Neuf 654.00 588.60 H.T.

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Détails Produit

Avanti Mini Extruder allows researchers and scientists to prepare large, unilamellar vesicles by extrusion in an efficient manner.Avanti Mini Extruder allows researchers and scientists to prepare large, unilamellar vesicles by extrusion in an efficient manner.

Convenient

  • Prepare large, unilameller vesicles (LUVs) by extrusion in an easy, rapid, and efficient manner.
  • Design allows for the rapid cleaning of all wetted parts, reducing “down-time” between production of vesicles from different lipid species
  • Generate uniform populations of unilamellar liposomes without the use of solvents or detergents
  • Vesicle size readily controlled by polycarbonate membrane selection

Affordable

The Avanti Mini-Extruder is constructed of stainless steel and Teflon; the new design is guaranteed to give years of trouble-free service and is available for a fraction of the cost of a larger extruder.

  • Available for a fraction of the cost of a larger extruder
  • All parts/replacement parts are available from Avanti
  • Set includes:
    • Mini Extruder
    • 2 O-Rings
    • 2 Gas Tight syringes (1000 µL)
    • 100 Polycarbonate Membranes (0.1 µm)
    • 100 Filter supports

Flexible

Placing the stabilizer block-extruder assembly on a hot plate achieves rapid temperature control for lipids that have transition temperatures above room temperature.

  • Optional heating block allows the extrusion of vesicles at elevated temperatures, which is critical for the successful production of vesicles from phospholipids with a phase transition temperature above room temperature
  • Generate unilamellar liposomes ranging from 30nm-1 µm when assembled with appropriate polycarbonate membrane
  • Useful for a wide variety of lipid composition
  • Interchangeable with 250 µL and 1 mL syringes

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Reliable

The particle size distribution of unilamellar vesicles prepared by extrusion is a function of the number of passes through the extruder membrane.

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Hydrated lipid solutions will initially form large, multilamellar vesicles. After the initial pass through a membrane, the particle size distribution will tend towards bimodal. After sufficient passes through the membrane, a unimodal, normal distribution is obtained. A minimum of eleven passes through the extruder membrane is recommended for most lipids.

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Placing the heating block assembly on a hot plate achieves rapid temperature control for lipids that have transition temperatures above room temperature.

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