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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Product Description
Pure lectin GNL/GNA is isolated from snowdrop bulbs, Galanthus nivalis and purified by affinity chromatography. GNL consists of four identical subunits with a molecular weight of 50,000 and isoelectric points between pH 3.5 and 4. This lectin is known to agglutinate rabbit erythrocytes but not human erythrocytes. GNL contains little to no carbohydrate and specifically binds to murine IgM immunoglobin and human α2-macroglobulin, but not to alpha-linked glucose (unlike majority of mannose-binding lectins). Structures containing (α-1,3) mannose residues are preferred for binding and elutes a concentration of 0.2M of MeαMannose. GNL is useful for HIV research, applicable for blood cell agglutination studies, and has set a model system to help understand the molecular basis of how proteins recognize carbohydrates.
This product comes in a lyophilized powder form and is stable for over five years from production date when stored below -20 C. EEL does not need metal ions for binding.
Applications:
HIV research
Blood cell agglutination studies
Model systems to help understand the molecular basis of how proteins recognize carbohydrates
References
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